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including publications from previous affiliations

Okuda S. (2022) Structural insight of peptide-ligand recognition by plant membrane receptors., Plant Morphology, 34, 29-36.

Kaneshiro I. Igarashi M., Higashiyama T., Mizuta Y. (2022) Target pollen isolation using automated infrared laser-mediated cell disruption. Quant. Plant Biol. 3, e30.

Takeda S., Hamamura Y., Sakamoto T., Kimura S., Aida M., Higashiyama T. (2022) Non-cell-autonomous regulation of petal initiation in Arabidopsis thaliana. Development 149, dev200684.

Nakajima K.P., Valansi C., Kurihara D., Sasaki N., Podbilewicz B., Higashiyama T. (2022) Live imaging-based assay for visualising species-specific interactions in gamete adhesion molecules. Sci. Reports 12, 9609.

Kumarswamyreddy N., Reddy D.N., Robkis D.M., Kamiya N, Tsukamoto R., Kanaoka M.M., Higashiyama T., Oishi S., Bode J.W. (2022) Chemical synthesis of Torenia plant pollen tube attractant proteins by KAHA ligation. RSC Chem. Biol. 3, 721-727.
DOI: 10.1039/D2CB00039C

Nagae T.T., Takeuchi H., Higashiyama T. (2022) Quantification of Species-Preferential Micropylar Chemoattraction in Arabidopsis by Fluorescein Diacetate Staining of Pollen Tubes. Int J Mol Sci. 23, 2722.

Urakawa N., Nakamura S., Kishimoto M., Moriyama Y., Kawano S., Higashiyama T., Sasaki N. (2022) Semi-in vitro detection of Mg2+-dependent DNase that specifically digest mitochondrial nucleoids in the zygote of Physarum polycephalum. Sci. Reports 12, 2995.

Urakawa N., Uno K., Sato Y., Higashiyama T., Sasaki N. (2022) Rapid selective proliferation of mitochondria during zygote maturation in the uniparental inheritance of Physarum polycephalum. Cytologia 87, 163-168.



including publications from previous affiliations

東山哲也(2021)花の中での知られざる情報処理.情報処理 62, e4-e6.

Higashiyama T., Maizel A., Simon R. (2021) Seeing is believing: Advances in Plant Imaging Technologies. Plant Cell Physiol. 62, 1217-1220.

Yanagisawa N., Kozgunova E., Grossmann G., Geitmann A., Higashiyama T. (2021) Microfluidics-based Bioassays and Imaging of Plant Cells. Plant Cell Physiol. 62, 1239-1250.

Nomoto M., Skelly M.J., Itaya T., Mori T., Suzuki T., Matsushita T., Tokizawa M., Kuwata K., Mori H., Yamamoto Y.Y., Higashiyama T., Tsukagoshi H., Spoel S.H., Tada Y. (2021) Suppression of MYC transcription activators by the immune cofactor NPR1 fine-tunes plant immune responses. Cell Rep. 14, 110125.

Aini H., Sato Y., Uno K., Higashiyama T., Okamoto T. (2021) Dynamics of mitochondrial distribution during development and asymmetric division of rice zygotes. Plant Reprod. 35, 47-60.

Yanagisawa N., Kozgunova E., Higashiyama T. (2021) Pulsatile reverse flow actuated microfluidic injector: toward the application for single-molecule chemotropism assay. RSC Adv. 11, 27011-27018.

Tanaka, N., Mogi, Y., Fujiwara, T., Yabe, K., Toyama, Y., Higashiyama, T. and Yoshida, Y. (2021) CZON-cutter – a CRISPR-Cas9 system for multiplexed organelle imaging in a simple unicellular alga. Journal of Cell Science 134, 1-11

Matsumoto H., Kimata Y., Higaki T., Higashiyama T., Ueda M. (2021) Dynamic Rearrangement and Directional Migration of Tubular Vacuoles are Required for the Asymmetric Division of the Arabidopsis Zygote. Plant Cell Physiol. 62, 1280-1289.

Kimata Y., Higaki T., Kurihara D., Ando N., Matsumoto H., Higashiyama T., Ueda M. (2021) Mitochondrial dynamics and segregation during the asymmetric division of Arabidopsis zygotes. Quant. Plant Biol. 1, e3
doi: 10.1017/qpb.2020.4

Takahashi K., Kawai-Toyooka H., Ootsuki R., Hamaji T., Tsuchikane Y., Sekimoto H., Higashiyama T., Nozaki H. (2021) Three sex phenotypes in a haploid algal species give insights into the evolutionary transition to a self-compatible mating system. Evolution, 75, 2984-2993.

Tanaka, N., Mogi, Y., Fujiwara, T., Yabe, K., Toyama, Y., Higashiyama, T. and Yoshida, Y. (2021) CZON-cutter – a CRISPR-Cas9 system for multiplexed organelle imaging in a simple unicellular alga. Journal of Cell Science 134, 1-11

Kurihara D., Mizuta Y., Nagahara S., Higashiyama T. (2021) ClearSeeAlpha: Advanced Optical Clearing for Whole-Plant Imaging. Plant Cell Physiol., 62,1302-1310.

Okuda S. (2021) Molecular mechanisms of plant peptide binding to receptors. Peptides 144, 170614

Windari E.A., Ando M., Mizoguchi Y., Shimada H., Ohira K., Kagaya Y., Higashiyama T., Takayama S., Watanabe M., Suwabe K. (2021) Two aquaporins, SIP1;1 and PIP1;2, mediate water transport for pollen hydration in the Arabidopsis pistil. Plant Biotech. 38, 77-87.

Motomura K., Takeuchi H., Notaguchi M., Tsuchi H., Takeda A., Kinoshita T., Higashiyama T., Maruyama D. (2021) Persistent directional growth capability in Arabidopsis thaliana pollen tubes after nuclear elimination from the apex. Nat. Commun. 12, 2331.

Susaki D., Daisuke M., Minako U., Higashiyama T., Kurihara D. (2021) Dynamics of the cell fate specifications during female gametophyte development in Arabidopsis. PLoS Biol. 19, e3001123.

Nagahara S., Takeuchi H., Higashiyama T. (2021) Polyspermy Block in the Central Cell during Double Fertilization of Arabidopsis thaliana. Front. Plant Sci. 11, 588700.



including publications from previous affiliations

Su S., Nagae T.T., Higashiyama T. (2020) GPI-Anchored Proteins Cooperate in the Long Journey of the Pollen Tube. Mol. Plant 13, 8-10.

Crook A D, Willoughby A C, Hazak O, Okuda S, VanDerMolen K R, Soyars C L, Cattaneo P, Clark N M, Sozzani R, Hothorn M, Hardtke C S, Nimchuk Z L (2020) BAM1/2 receptor kinase signaling drives CLE peptide-mediated formative cell divisions in Arabidopsis roots. Proc Natl Acad Sci U S A 117 (51) 32750-32756.

Steinbrenner A D, Muñoz-Amatriaín M, Chaparro A F, Aguilar-Venegas J M, Lo S, Okuda S, Glauser G, Dongiovanni J, Shi D, Hall M, Crubaugh D, Holton N, Zipfel C, Abagyan R, Turlings T C J, Close T J, Huffaker A, Schmelz E A (2020) A receptor-like protein mediates plant immune responses to herbivore-associated molecular patterns. Proc Natl Acad Sci U S A 117(49):31510-31518.

Kimata Y., Higaki T., Kurihara D., Ando N., Matsumoto H., Higashiyama T., Ueda M. (2020) Mitochondrial dynamics and segregation during the asymmetric division of Arabidopsis zygotes. Quant. Plant Biol. 1, e3

Nishikawa S., Yamaguchi Y., Suzuki C., Yabe A., Sato Y., Kurihara D., Sato Y., Susaki D., Higashiyama T., Maruyama D. (2020) Arabidopsis GEX1 is a nuclear membrane protein of gametes required for nuclear fusion during reproduction. Front. Plant Sci. 11, 548032.

Kawamoto N., Del Carpio D.P., Hofmann A., Mizuta Y., Kurihara D., Higashiyama T., Uchida N., Torii K.U., Colombo L., Groth G., Simon R. (2020) A peptide pair coordinates regular ovule initiation patterns with seed number and fruit size. Curr. Biol. 30, 4352-4361.

Notaguchi M., Kurotani K., Sato Y., Tabata R., Kawakatsu Y., Okayasu K., Sawai Y., Okada R., Asahina M., Ichihashi Y., Shirasu K., Suzuki T., Niwa M., Higashiyama T. (2020) Cell–cell adhesion in plant grafting is facilitated by β-1,4-glucanases. Science 369, 698-702.

Tsutsui H., Yanagisawa N., Kawakatsu Y., Ikematsu S., Sawai Y., Tabata R., Arata H., Higashiyama T., Notaguchi M. (2020) Micrografting device for testing systemic signaling in Arabidopsis. Plant J. 103, 918-929.

Borg M., Jacob Y., Susaki D., LeBlanc C., Buendía D., Axelsson E., Kawashima T., Voigt P., Boavida L., Becker J., Higashiyama T., Martienssen R., Berger F. (2020) Targeted reprogramming of H3K27me3 resets epigenetic memory in plant paternal chromatin. Nature Cell Biol. 22, 621-629.

Motomura K., Arae T., Uramoto H.A., Suzuki Y., Takeuchi H., Suzuki T., Ichihashi Y., Shibata A., Shirasu K., Takeda A., Higashiyama T., Chiba Y. (2020) AtNOT1 is a novel regulator of gene expression during pollen development. Plant Cell Physiol. 61, 712-721. COVER OF THE ISSUE

Nakano S., Ikeda M., Tsukada Y., Fei X., Suzuki T., Niino Y., Ahluwalia R., Sano A., Kondo R., Ihara K., Miyawaki A., Hashimoto K., Higashiyama T., Mori I. (2020) Presynaptic MAST kinase controls opposing postsynaptic responses to convey stimulus valence in Caenorhabditis elegans. Proc. Natl. Acad. Sci. USA 117, 1638-1647.

Liu X., Wu X., Adhikari P.B., Zhu S., Kinoshita Y., Berger F., Higashiyama T., Kasahara R.D. (2020) Establishment of a novel method for the identification of fertilization defective mutants in Arabidopsis thaliana. Biochem Biophys Res Commun. 521, 928-932.

Maruyama D., Higashiyama T., Endo T., Nishikawa S. (2020) Fertilization-Coupled Sperm Nuclear Fusion is Required for Normal Endosperm Nuclear Proliferation. Plant Cell Physiol. 61, 29-40. COVER OF THE ISSUE

Luo L., Ando S., Sakamoto Y., Suzuki T., Takahashi H., Ishibashi N., Kojima S., Kurihara D., Higashiyama T., Yamamoto K. T., Matsunaga S., Machida C., Sasabe M., Machida Y. (2020) The formation of perinucleolar bodies is important for normal leaf development and requires the zinc-finger DNA-binding motif in Arabidopsis ASYMMETRIC LEAVES2. Plant J., 101, 1118-1134.



including publications from previous affiliations

Tsutsui H., Sato Y., Susaki D., Higashiyama T. (2019) Microtubule depletion domain 1 localizes at the boundary between female gametes in Arabidopsis thaliana. Mol. Reprod. Dev. 86, 925

Nozoye T., von Wiren N., Sato Y., Higashiyama T., Nakanishi H., Nishizawa N.K. (2019) Characterization of the nicotianamine exporter ENA1 in rice. Front. Plant Sci. 10, 502.

Maki H., Sakaoka S., Itaya T., Suzuki T., Mabuchi K., Amabe T., Suzuki N., Higashiyama T., Tada Y., Nakagawa T., Morikami A., Tsukagoshi H. (2019) ANAC032 regulates root growth through the MYB30 gene regulatory network. Sci. Reports 9, 11358.

Kimata Y., Kato T., Higaki T., Kurihara D., Yamada T., Segami S., Morita M.T., Maeshima M., Hasezawa S., Higashiyama T., Tasaka M. Ueda M. (2019) Polar vacuolar distribution is essential for accurate asymmetric division of Arabidopsis zygotes. Proc. Natl. Acad. Sci. USA 116, 2338-2343.

Ohno M., Ando T., Priest D.G., Kumar V., Yoshida Y., Taniguchi Y. (2019) Sub-nucleosomal genome structure reveals distinct nucleosome folding motifs. Cell 176, 520-534.e25.

Yoshida Y., Mogi Y. (2019) How do plastids and mitochondria divide? Microscopy 68, 45-56.

Xiao W., Su S., Higashiyama T., Luo D. (2019) A homolog of the ALOG family controls corolla tube differentiation in Torenia fournieri. Development 146, dev177410.

Yoshida Y., Taniguchi Y. (2019) Simultaneous single-cell measurements demonstrate a positive correlation between RNA copy number for mitochondrial division and fusion genes and mitochondrial fragmentation. Cytologia 84, 15–23.

Yamamoto S., Uchida Y., Ohtani T., Nozaki E., Yin C., Goto Y., Kaminatsui N., Higashiyama T., Suzuki T., Takemoto T., Shiraishi Y., Kuroiwa A. (2019) Hoxa13 regulates the expression of common Hox target genes involved in cartilage development to coordinate the expansion of the autopod anlagen. Dev. Growth Differ. 61, 228-251.

Kurita K., Sakamoto Y., Naruse S., Matsunaga T.M., Arata H., Higashiyama T., Habu Y., Utsumi Y., Utsumi C., Tanaka M., Takahashi S., Kim J.M., Seki M., Sakamoto T., Matsunaga S. (2019) Intracellular localization of histone deacetylase HDA6 in plants. J. Plant Res. 132, 629-640.

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